閻作勤，男，主任醫(yī)師，教授，副院長(zhǎng)，博士生導(dǎo)師，中華創(chuàng)傷學(xué)會(huì)委員，上海創(chuàng)傷分會(huì)主任委員，中華骨科學(xué)分會(huì)關(guān)節(jié)學(xué)組委員． 具有豐富的臨床經(jīng)驗(yàn)，尤其擅長(zhǎng)微創(chuàng)人工關(guān)節(jié)置換技術(shù)以及先天性畸形、髖關(guān)節(jié)發(fā)育不好、股骨頭壞死的診治，并開(kāi)展了一些新的技術(shù)：1、2003年上海市較早開(kāi)展了骨髓基質(zhì)干細(xì)胞股骨頭壞死的臨床研究；2、在國(guó)內(nèi)較早引進(jìn)T-SAW，進(jìn)行椎板大塊切除回植治療椎管內(nèi)腫瘤，獲得了良好的，在此基礎(chǔ)上，改進(jìn)Tomita大塊切除椎體腫瘤技術(shù)，針對(duì)手術(shù)過(guò)程中存在的問(wèn)題，設(shè)計(jì)了專門器械（已申請(qǐng)專利），簡(jiǎn)化作難度，降低手術(shù)危險(xiǎn)，提高了手術(shù)的靠譜性，大大提高了脊柱腫瘤的治療水平(包括原發(fā)性和轉(zhuǎn)移性），降低了并發(fā)癥的發(fā)生。 申請(qǐng)人作為項(xiàng)目負(fù)責(zé)人承擔(dān)上海市課題和上海市自然科學(xué)基金二項(xiàng)，作為第三參與者參加自然科學(xué)基金、973子課題項(xiàng)目的科研工作。參加編寫(xiě)或編譯的專著有：《實(shí)用外科學(xué)》、《脊柱創(chuàng)傷外科學(xué)》、《實(shí)用骨科手冊(cè)》、《周圍神經(jīng)損傷基礎(chǔ)與臨床研究》、《外科手術(shù)并發(fā)癥的預(yù)防與處理》、《O’connor關(guān)節(jié)鏡外科學(xué)》等。2006年主譯出版了66萬(wàn)字的《脊柱外科手術(shù)圖譜》專著一本。獲得3項(xiàng)發(fā)明專利授權(quán)，申請(qǐng)一項(xiàng)專利。在骨科領(lǐng)域核心期刊發(fā)表論文40余篇，近5年發(fā)表18篇，其中SCI論文6篇，核心期刊11篇。在股骨頭壞死研究方面發(fā)表SCI論文兩篇（IF2.9,2.7），在國(guó)際上首先發(fā)現(xiàn)采用利福平增強(qiáng)P-gp的活性有助于降低激素性壞死的發(fā)生，論文發(fā)表在國(guó)際的期刊Calsif Tissue International，為降低激素性股骨頭壞死的發(fā)生提出了一種新的思路。 1. Predictive value of single photon emission computerized tomography and computerized tomography in osteonecrosis after femoral neck fracture: a prospective study. Yuan HF, Shen F, Zhang J, Shi HC, Gu YS, Yan ZQ. Int Orthop. 2015 Feb 25. [Epub ahead of print] PMID:25711398 2. Protective effects of total saponins of panax notoginseng on steroid-induced avascular necrosis of the femoral head in vivo and in vitro. Yuan HF, Pan JF, Li S, Guo CA, Liu SH, Yan ZQ. Evid Based Complement Alternat Med. 2015;2015:165679. doi: 10.1155/2015/165679. Epub 2015 Jan 28. PMID: 25694788 3. Analysis of altered microRNA expression profile in the reparative interface of the femoral head with osteonecrosis. Yuan HF, Von Roemeling C, Gao HD, Zhang J, Guo CA, Yan ZQ. Exp Mol Pathol. 2015 Apr;98(2):158-63. doi: 10.1016/j.yexmp.2015.01.002. 4. Mediopatellar plica as a risk factor for knee osteoarthritis? Yuan HF, Guo CA, Yan ZQ. Chin Med J (Engl). 2015 Jan 20;128(2):277-8. doi: 10.4103/0366-6999.149237. No abstract available. PMID:25591575 5. A "two-incision" approach for en bloc resection of periacetabular tumors with illustrations from a cadaver. Guo CA, Yan ZQ. Orthop Surg. 2014 Feb;6(1):60-4. doi: 10.1111/os.12094. 6.Modified total En-bloc spondylectomy in thoracic vertebra tumour European Spine Journal 2010 DOI: 10.1007/s00586-010-1618-0 7.Effects of P-Glycoprotein on Steroid-Induced Osteonecrosis of the Femoral Head Calcif Tissue Int (2010) 87:246–253 8.Effect of rifampicin on the risk of steroid-induced osteonecrosis of th femoral head. Orthopaedic Surgery 2010,2(2):124-133 9.Failure of xenoimplantation using porcine synovium-derived stem cell-based cartilage tissue constructs for the repair of rabbit osteochondral defects. J Orthop Res 2010，28:1064–1070, 10.Fate of mesenchymal stem cells transplanted to osteonecrosis of femoral head. J Orthop Res 2009, 27(4):442-446. 11.Treatment of osteonecrosis of the femoral head by percutaneous decompression and autologous bone marrow mononuclear cell infusion.Chinese J. of Traumatology 2006,2(1):3-7.